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Anti-Apoptotic Effects of Recombinant Human Hepatocyte Growth Factor on Hepatocytes Were Associated with Intrahepatic Hemorrhage Suppression Indicated by the Preservation of Prothrombin Time
Hepatocyte growth factor (HGF) is an endogenously expressed bioactive substance that has a strong anti-apoptotic effect. In this study, we biochemically and histologically characterized the effects of rh-HGF on in vitro human hepatocyte injury and mouse acute liver failure (ALF) models, both of whic...
Autores principales: | Motoi, Sotaro, Toyoda, Hiroko, Obara, Takashi, Ohta, Etsuko, Arita, Yoshihisa, Negishi, Kana, Moriya, Katsuhiro, Kuboi, Yoshikazu, Soejima, Motohiro, Imai, Toshio, Ido, Akio, Tsubouchi, Hirohito, Kawano, Tetsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514566/ https://www.ncbi.nlm.nih.gov/pubmed/31013780 http://dx.doi.org/10.3390/ijms20081821 |
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