Cargando…

Rosmarinic Acid Attenuates Cadmium-Induced Nephrotoxicity via Inhibition of Oxidative Stress, Apoptosis, Inflammation and Fibrosis

The present investigation was executed to reveal the protective mechanism of rosmarinic acid (RA) against cadmium (Cd)-induced nephrotoxicity. RA exhibited a concentration-dependent anti-apoptotic effect against CdCl(2) in isolated mouse proximal tubular epithelial cells. Cd treatment significantly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Joardar, Swarnalata, Dewanjee, Saikat, Bhowmick, Shovonlal, Dua, Tarun K., Das, Sonjit, Saha, Achintya, De Feo, Vincenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514581/ https://www.ncbi.nlm.nih.gov/pubmed/31022990 http://dx.doi.org/10.3390/ijms20082027

Ejemplares similares

Carnosic Acid Attenuates Cadmium Induced Nephrotoxicity by Inhibiting Oxidative Stress, Promoting Nrf2/HO-1 Signalling and Impairing TGF-β1/Smad/Collagen IV Signalling
por: Das, Sonjit, et al.
Publicado: (2019)

Carnosic Acid, a Natural Diterpene, Attenuates Arsenic-Induced Hepatotoxicity via Reducing Oxidative Stress, MAPK Activation, and Apoptotic Cell Death Pathway
por: Das, Sonjit, et al.
Publicado: (2018)

Myricitrin, a Glycosyloxyflavone in Myrica esculenta Bark Ameliorates Diabetic Nephropathy via Improving Glycemic Status, Reducing Oxidative Stress, and Suppressing Inflammation
por: Dua, Tarun K., et al.
Publicado: (2021)

Protocatechuic Acid, a Phenolic from Sansevieria roxburghiana Leaves, Suppresses Diabetic Cardiomyopathy via Stimulating Glucose Metabolism, Ameliorating Oxidative Stress, and Inhibiting Inflammation
por: Bhattacharjee, Niloy, et al.
Publicado: (2017)

Cytoprotective and Antioxidant Effects of an Edible Herb, Enhydra fluctuans Lour. (Asteraceae), against Experimentally Induced Lead Acetate Intoxication
por: Dua, Tarun K., et al.
Publicado: (2016)

Natural Products as Alternative Choices for P-Glycoprotein (P-gp) Inhibition
por: Dewanjee, Saikat, et al.
Publicado: (2017)

Water Spinach, Ipomoea aquatica (Convolvulaceae), Ameliorates Lead Toxicity by Inhibiting Oxidative Stress and Apoptosis
por: Dewanjee, Saikat, et al.
Publicado: (2015)

The effects of two common edible herbs, Ipomoea aquatica and Enhydra fluctuans, on cadmium-induced pathophysiology: a focus on oxidative defence and anti-apoptotic mechanism
por: Dua, Tarun K, et al.
Publicado: (2015)

Sansevieria roxburghiana Schult. & Schult. F. (Family: Asparagaceae) Attenuates Type 2 Diabetes and Its Associated Cardiomyopathy
por: Bhattacharjee, Niloy, et al.
Publicado: (2016)

Abroma augusta L. (Malvaceae) leaf extract attenuates diabetes induced nephropathy and cardiomyopathy via inhibition of oxidative stress and inflammatory response
por: Khanra, Ritu, et al.
Publicado: (2015)

Effects of Rosmarinic Acid on Methotrexate-induced Nephrotoxicity and Hepatotoxicity in Wistar Rats
por: Jafaripour, Leila, et al.
Publicado: (2021)

Royal jelly attenuates cadmium-induced nephrotoxicity in male mice
por: Almeer, Rafa S., et al.
Publicado: (2019)

Structure-based identification of SARS-CoV-2 main protease inhibitors from anti-viral specific chemical libraries: an exhaustive computational screening approach
por: Bhowmick, Shovonlal, et al.
Publicado: (2021)

Cadmium Transporters in the Kidney and Cadmium-Induced Nephrotoxicity
por: Yang, Hong, et al.
Publicado: (2015)

Ameliorative effect of water spinach, Ipomea aquatica (Convolvulaceae), against experimentally induced arsenic toxicity
por: Dua, Tarun K, et al.
Publicado: (2015)

Probiotics: Evolving as a Potential Therapeutic Option against Acetaminophen-Induced Hepatotoxicity
por: Dewanjee, Saikat, et al.
Publicado: (2022)

Cadmium and Lead Exposure, Nephrotoxicity, and Mortality
por: Satarug, Soisungwan, et al.
Publicado: (2020)

Biologic indicators of cadmium nephrotoxicity in persons with low-level cadmium exposure.
por: Nogawa, K
Publicado: (1984)

Urinary metallothionein as an indicator of cadmium body burden and of cadmium-induced nephrotoxicity.
por: Shaikh, Z A, et al.
Publicado: (1984)

Identification of potent food constituents as SARS-CoV-2 papain-like protease modulators through advanced pharmacoinformatics approaches
por: Bhowmick, Shovonlal, et al.
Publicado: (2022)

Identification of bio-active food compounds as potential SARS-CoV-2 PLpro inhibitors-modulators via negative image-based screening and computational simulations
por: Bhowmick, Shovonlal, et al.
Publicado: (2022)

Structure-based identification of galectin-1 selective modulators in dietary food polyphenols: a pharmacoinformatics approach
por: Bhowmick, Shovonlal, et al.
Publicado: (2021)

Live and Let Die: Roles of Autophagy in Cadmium Nephrotoxicity
por: Thévenod, Frank, et al.
Publicado: (2015)

A Comparison of the Nephrotoxicity of Low Doses of Cadmium and Lead
por: Satarug, Soisungwan, et al.
Publicado: (2020)

Evaluation of cystatin C as an early biomarker of cadmium nephrotoxicity in the rat
por: Prozialeck, Walter C., et al.
Publicado: (2015)

In vitro nephrotoxicity and anticancer potency of newly synthesized cadmium complexes
por: Abyar, Selda, et al.
Publicado: (2019)

Effective Control of Type 2 Diabetes through Antioxidant Defense by Edible Fruits of Diospyros peregrina
por: Dewanjee, Saikat, et al.
Publicado: (2011)

Bioautography and its scope in the field of natural product chemistry
por: Dewanjee, Saikat, et al.
Publicado: (2015)

Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling
por: Zhang, Xin, et al.
Publicado: (2018)

New approaches for detecting thresholds of human nephrotoxicity using cadmium as an example.
por: Mueller, P W, et al.
Publicado: (1998)

Combining Patulin with Cadmium Induces Enhanced Hepatotoxicity and Nephrotoxicity In Vitro and In Vivo
por: Cui, Jinling, et al.
Publicado: (2021)

Rosmarinic Acid Attenuates Airway Inflammation and Hyperresponsiveness in a Murine Model of Asthma
por: Liang, Zhengmin, et al.
Publicado: (2016)

Muscle Cell Insulin Resistance Is Attenuated by Rosmarinic Acid: Elucidating the Mechanisms Involved
por: Den Hartogh, Danja J., et al.
Publicado: (2023)

Arbutin attenuates nephrotoxicity induced by gentamicin
por: Emadi, Elnaz, et al.
Publicado: (2021)

Subcellular targets of cadmium nephrotoxicity: cadmium binding to renal membrane proteins in animals with or without protective metallothionein synthesis.
por: Nordberg, G F, et al.
Publicado: (1994)

Plant-Based Antidiabetic Nanoformulations: The Emerging Paradigm for Effective Therapy
por: Dewanjee, Saikat, et al.
Publicado: (2020)

Asperuloside attenuates cadmium-induced toxicity by inhibiting oxidative stress, inflammation, fibrosis and apoptosis in rats
por: Kong, Zhiyang, et al.
Publicado: (2023)

Modulatory effect of protocatechuic acid on cadmium induced nephrotoxicity and hepatoxicity in rats in vivo
por: Adefegha, Stephen A., et al.
Publicado: (2015)

Cadmium Nephrotoxicity Is Associated with Altered MicroRNA Expression in the Rat Renal Cortex
por: Fay, Michael J., et al.
Publicado: (2018)

Estimation of the Cadmium Nephrotoxicity Threshold from Loss of Glomerular Filtration Rate and Albuminuria
por: Satarug, Soisungwan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_l1mopsbrq5midbv4gdloei8e68