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The Effects of Astragalus membranaceus Active Extracts on Autophagy-Related Diseases
Autophagy is an evolutionarily conserved ‘self-eating’ process that maintains cellular, tissue, and organismal homeostasis. New studies on autophagy, mediated by subsets of autophagy proteins, are emerging in many physiological and pathological processes. Astragalus membranaceus (AM), also named Hua...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514605/ https://www.ncbi.nlm.nih.gov/pubmed/30999666 http://dx.doi.org/10.3390/ijms20081904 |
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author | Shan, Hao Zheng, Xueping Li, Min |
author_facet | Shan, Hao Zheng, Xueping Li, Min |
author_sort | Shan, Hao |
collection | PubMed |
description | Autophagy is an evolutionarily conserved ‘self-eating’ process that maintains cellular, tissue, and organismal homeostasis. New studies on autophagy, mediated by subsets of autophagy proteins, are emerging in many physiological and pathological processes. Astragalus membranaceus (AM), also named Huangqi, is one of the fundamental herbs in traditional Chinese medicine and its extracts have been proved to possess many biological activities related to autophagy, including anti-oxidation, anti-inflammation, anticancer, anti-photoaging, and improvement of cardiomyocyte function. Evidence suggests that AM extracts can have therapeutic potential in autophagy dysregulation-associated diseases because of their biological positive effects. Here we will review the literature concerning the effects of AM extracts on autophagy dysregulation-associated diseases. |
format | Online Article Text |
id | pubmed-6514605 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-65146052019-05-30 The Effects of Astragalus membranaceus Active Extracts on Autophagy-Related Diseases Shan, Hao Zheng, Xueping Li, Min Int J Mol Sci Review Autophagy is an evolutionarily conserved ‘self-eating’ process that maintains cellular, tissue, and organismal homeostasis. New studies on autophagy, mediated by subsets of autophagy proteins, are emerging in many physiological and pathological processes. Astragalus membranaceus (AM), also named Huangqi, is one of the fundamental herbs in traditional Chinese medicine and its extracts have been proved to possess many biological activities related to autophagy, including anti-oxidation, anti-inflammation, anticancer, anti-photoaging, and improvement of cardiomyocyte function. Evidence suggests that AM extracts can have therapeutic potential in autophagy dysregulation-associated diseases because of their biological positive effects. Here we will review the literature concerning the effects of AM extracts on autophagy dysregulation-associated diseases. MDPI 2019-04-17 /pmc/articles/PMC6514605/ /pubmed/30999666 http://dx.doi.org/10.3390/ijms20081904 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Shan, Hao Zheng, Xueping Li, Min The Effects of Astragalus membranaceus Active Extracts on Autophagy-Related Diseases |
title | The Effects of Astragalus membranaceus Active Extracts on Autophagy-Related Diseases |
title_full | The Effects of Astragalus membranaceus Active Extracts on Autophagy-Related Diseases |
title_fullStr | The Effects of Astragalus membranaceus Active Extracts on Autophagy-Related Diseases |
title_full_unstemmed | The Effects of Astragalus membranaceus Active Extracts on Autophagy-Related Diseases |
title_short | The Effects of Astragalus membranaceus Active Extracts on Autophagy-Related Diseases |
title_sort | effects of astragalus membranaceus active extracts on autophagy-related diseases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514605/ https://www.ncbi.nlm.nih.gov/pubmed/30999666 http://dx.doi.org/10.3390/ijms20081904 |
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