Structural and functional consequences of age-related isomerization in α-crystallins

Long-lived proteins are subject to spontaneous degradation and may accumulate a range of modifications over time, including subtle alterations such as side-chain isomerization. Recently, tandem MS has enabled identification and characterization of such peptide isomers, including those differing only...

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Detalles Bibliográficos
Autores principales: Lyon, Yana A., Collier, Miranda P., Riggs, Dylan L., Degiacomi, Matteo T., Benesch, Justin L. P., Julian, Ryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514633/
https://www.ncbi.nlm.nih.gov/pubmed/30804217
http://dx.doi.org/10.1074/jbc.RA118.007052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514633/
https://www.ncbi.nlm.nih.gov/pubmed/30804217
http://dx.doi.org/10.1074/jbc.RA118.007052

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