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Unveiling the Efficacy, Safety, and Tolerability of Anti-Interleukin-1 Treatment in Monogenic and Multifactorial Autoinflammatory Diseases
Autoinflammatory diseases (AIDs) are heterogeneous disorders characterized by dysregulation in the inflammasome, a large intracellular multiprotein platform, leading to overproduction of interleukin-1(IL-1)β that plays a predominant pathogenic role in such diseases. Appropriate treatment is crucial,...
Autores principales: | Bettiol, Alessandra, Lopalco, Giuseppe, Emmi, Giacomo, Cantarini, Luca, Urban, Maria Letizia, Vitale, Antonio, Denora, Nunzio, Lopalco, Antonio, Cutrignelli, Annalisa, Lopedota, Angela, Venerito, Vincenzo, Fornaro, Marco, Vannacci, Alfredo, Rigante, Donato, Cimaz, Rolando, Iannone, Florenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514653/ https://www.ncbi.nlm.nih.gov/pubmed/30999610 http://dx.doi.org/10.3390/ijms20081898 |
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