Oxytrodiflavanone A and Oxytrochalcoflavanones A,B: New Biflavonoids from Oxytropis chiliophylla

Three previously undescribed biflavonoids, oxytrodiflavanone A (1), and oxytrochalcoflavanones A,B (2,3), were isolated from the aerial part of Oxytropis chiliophylla, together with their putative biosynthetic monomers, i.e., (2S)-5,7-dihydroxyflavanone (4), (2S)-7-hydroxyflavanone (5), and 2′,4′-di...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yang, Kelsang, Norbo, Lu, Jianghai, Zhang, Yingtao, Liang, Hong, Tu, Pengfei, Kong, Dexin, Zhang, Qingying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514731/
https://www.ncbi.nlm.nih.gov/pubmed/31013944
http://dx.doi.org/10.3390/molecules24081468
_version_ 1783417928989802496
author Liu, Yang
Kelsang, Norbo
Lu, Jianghai
Zhang, Yingtao
Liang, Hong
Tu, Pengfei
Kong, Dexin
Zhang, Qingying
author_facet Liu, Yang
Kelsang, Norbo
Lu, Jianghai
Zhang, Yingtao
Liang, Hong
Tu, Pengfei
Kong, Dexin
Zhang, Qingying
author_sort Liu, Yang
collection PubMed
description Three previously undescribed biflavonoids, oxytrodiflavanone A (1), and oxytrochalcoflavanones A,B (2,3), were isolated from the aerial part of Oxytropis chiliophylla, together with their putative biosynthetic monomers, i.e., (2S)-5,7-dihydroxyflavanone (4), (2S)-7-hydroxyflavanone (5), and 2′,4′-dihydroxychalcone (6). The structures of these compounds were elucidated by a combination analysis of spectroscopic data. The cytotoxic activities of all the isolated compounds against PC-3 human prostate cancer cell line are also presented.
format Online
Article
Text
id pubmed-6514731
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-65147312019-05-30 Oxytrodiflavanone A and Oxytrochalcoflavanones A,B: New Biflavonoids from Oxytropis chiliophylla Liu, Yang Kelsang, Norbo Lu, Jianghai Zhang, Yingtao Liang, Hong Tu, Pengfei Kong, Dexin Zhang, Qingying Molecules Article Three previously undescribed biflavonoids, oxytrodiflavanone A (1), and oxytrochalcoflavanones A,B (2,3), were isolated from the aerial part of Oxytropis chiliophylla, together with their putative biosynthetic monomers, i.e., (2S)-5,7-dihydroxyflavanone (4), (2S)-7-hydroxyflavanone (5), and 2′,4′-dihydroxychalcone (6). The structures of these compounds were elucidated by a combination analysis of spectroscopic data. The cytotoxic activities of all the isolated compounds against PC-3 human prostate cancer cell line are also presented. MDPI 2019-04-13 /pmc/articles/PMC6514731/ /pubmed/31013944 http://dx.doi.org/10.3390/molecules24081468 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Liu, Yang
Kelsang, Norbo
Lu, Jianghai
Zhang, Yingtao
Liang, Hong
Tu, Pengfei
Kong, Dexin
Zhang, Qingying
Oxytrodiflavanone A and Oxytrochalcoflavanones A,B: New Biflavonoids from Oxytropis chiliophylla
title Oxytrodiflavanone A and Oxytrochalcoflavanones A,B: New Biflavonoids from Oxytropis chiliophylla
title_full Oxytrodiflavanone A and Oxytrochalcoflavanones A,B: New Biflavonoids from Oxytropis chiliophylla
title_fullStr Oxytrodiflavanone A and Oxytrochalcoflavanones A,B: New Biflavonoids from Oxytropis chiliophylla
title_full_unstemmed Oxytrodiflavanone A and Oxytrochalcoflavanones A,B: New Biflavonoids from Oxytropis chiliophylla
title_short Oxytrodiflavanone A and Oxytrochalcoflavanones A,B: New Biflavonoids from Oxytropis chiliophylla
title_sort oxytrodiflavanone a and oxytrochalcoflavanones a,b: new biflavonoids from oxytropis chiliophylla
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514731/
https://www.ncbi.nlm.nih.gov/pubmed/31013944
http://dx.doi.org/10.3390/molecules24081468
work_keys_str_mv AT liuyang oxytrodiflavanoneaandoxytrochalcoflavanonesabnewbiflavonoidsfromoxytropischiliophylla
AT kelsangnorbo oxytrodiflavanoneaandoxytrochalcoflavanonesabnewbiflavonoidsfromoxytropischiliophylla
AT lujianghai oxytrodiflavanoneaandoxytrochalcoflavanonesabnewbiflavonoidsfromoxytropischiliophylla
AT zhangyingtao oxytrodiflavanoneaandoxytrochalcoflavanonesabnewbiflavonoidsfromoxytropischiliophylla
AT lianghong oxytrodiflavanoneaandoxytrochalcoflavanonesabnewbiflavonoidsfromoxytropischiliophylla
AT tupengfei oxytrodiflavanoneaandoxytrochalcoflavanonesabnewbiflavonoidsfromoxytropischiliophylla
AT kongdexin oxytrodiflavanoneaandoxytrochalcoflavanonesabnewbiflavonoidsfromoxytropischiliophylla
AT zhangqingying oxytrodiflavanoneaandoxytrochalcoflavanonesabnewbiflavonoidsfromoxytropischiliophylla

Ejemplares similares