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CAR-T with License to Kill Solid Tumors in Search of a Winning Strategy

Artificial receptors designed for adoptive immune therapies need to absolve dual functions: antigen recognition and abilities to trigger the lytic machinery of reprogrammed effector T lymphocytes. In this way, CAR-T cells deliver their cytotoxic hit to cancer cells expressing targeted tumor antigens...

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Detalles Bibliográficos
Autores principales:	Sacchetti, Benedetto, Botticelli, Andrea, Pierelli, Luca, Nuti, Marianna, Alimandi, Maurizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514830/ https://www.ncbi.nlm.nih.gov/pubmed/30999624 http://dx.doi.org/10.3390/ijms20081903

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