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Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food
The inhibitory effects of baijiu vinasse extract and its phenolic acid compounds on the N(ε)-carboxymethyllysine (CML) formation from dairy food were investigated. The inhibitory effect of the baijiu vinasse extract against CML formation was 43.2% in the casein and D-glucose model, which used 6 mL o...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514854/ https://www.ncbi.nlm.nih.gov/pubmed/31003408 http://dx.doi.org/10.3390/molecules24081526 |
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author | Wang, Yuzhen Liu, Huilin Zhang, Dianwei Liu, Jingmin Wang, Jing Wang, Shuo Sun, Baoguo |
author_facet | Wang, Yuzhen Liu, Huilin Zhang, Dianwei Liu, Jingmin Wang, Jing Wang, Shuo Sun, Baoguo |
author_sort | Wang, Yuzhen |
collection | PubMed |
description | The inhibitory effects of baijiu vinasse extract and its phenolic acid compounds on the N(ε)-carboxymethyllysine (CML) formation from dairy food were investigated. The inhibitory effect of the baijiu vinasse extract against CML formation was 43.2% in the casein and D-glucose model, which used 6 mL of the 70% acetone extract at 60 °C for 40 min. The HPLC-MS/MS profiles of the vinasse extract indicated that vanillic, chlorogenic, p-coumaric, sinapic, caffeic, ferulic, and syringic acids were seven major phenolic acid compounds. Furthermore, the inhibitory mechanism of the phenolic acid compounds in the model of dairy food was discussed by the trapping and scavenging of glyoxal. The results of this study exhibit that seven major antioxidant phenolic acid compounds may play important roles in the antioxidant activity and CML inhibition of the vinasse extract in a model of dairy foods. |
format | Online Article Text |
id | pubmed-6514854 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-65148542019-05-30 Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food Wang, Yuzhen Liu, Huilin Zhang, Dianwei Liu, Jingmin Wang, Jing Wang, Shuo Sun, Baoguo Molecules Article The inhibitory effects of baijiu vinasse extract and its phenolic acid compounds on the N(ε)-carboxymethyllysine (CML) formation from dairy food were investigated. The inhibitory effect of the baijiu vinasse extract against CML formation was 43.2% in the casein and D-glucose model, which used 6 mL of the 70% acetone extract at 60 °C for 40 min. The HPLC-MS/MS profiles of the vinasse extract indicated that vanillic, chlorogenic, p-coumaric, sinapic, caffeic, ferulic, and syringic acids were seven major phenolic acid compounds. Furthermore, the inhibitory mechanism of the phenolic acid compounds in the model of dairy food was discussed by the trapping and scavenging of glyoxal. The results of this study exhibit that seven major antioxidant phenolic acid compounds may play important roles in the antioxidant activity and CML inhibition of the vinasse extract in a model of dairy foods. MDPI 2019-04-18 /pmc/articles/PMC6514854/ /pubmed/31003408 http://dx.doi.org/10.3390/molecules24081526 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wang, Yuzhen Liu, Huilin Zhang, Dianwei Liu, Jingmin Wang, Jing Wang, Shuo Sun, Baoguo Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food |
title | Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food |
title_full | Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food |
title_fullStr | Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food |
title_full_unstemmed | Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food |
title_short | Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food |
title_sort | baijiu vinasse extract scavenges glyoxal and inhibits the formation of n(ε)-carboxymethyllysine in dairy food |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514854/ https://www.ncbi.nlm.nih.gov/pubmed/31003408 http://dx.doi.org/10.3390/molecules24081526 |
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