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Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food

The inhibitory effects of baijiu vinasse extract and its phenolic acid compounds on the N(ε)-carboxymethyllysine (CML) formation from dairy food were investigated. The inhibitory effect of the baijiu vinasse extract against CML formation was 43.2% in the casein and D-glucose model, which used 6 mL o...

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Autores principales: Wang, Yuzhen, Liu, Huilin, Zhang, Dianwei, Liu, Jingmin, Wang, Jing, Wang, Shuo, Sun, Baoguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514854/
https://www.ncbi.nlm.nih.gov/pubmed/31003408
http://dx.doi.org/10.3390/molecules24081526
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author Wang, Yuzhen
Liu, Huilin
Zhang, Dianwei
Liu, Jingmin
Wang, Jing
Wang, Shuo
Sun, Baoguo
author_facet Wang, Yuzhen
Liu, Huilin
Zhang, Dianwei
Liu, Jingmin
Wang, Jing
Wang, Shuo
Sun, Baoguo
author_sort Wang, Yuzhen
collection PubMed
description The inhibitory effects of baijiu vinasse extract and its phenolic acid compounds on the N(ε)-carboxymethyllysine (CML) formation from dairy food were investigated. The inhibitory effect of the baijiu vinasse extract against CML formation was 43.2% in the casein and D-glucose model, which used 6 mL of the 70% acetone extract at 60 °C for 40 min. The HPLC-MS/MS profiles of the vinasse extract indicated that vanillic, chlorogenic, p-coumaric, sinapic, caffeic, ferulic, and syringic acids were seven major phenolic acid compounds. Furthermore, the inhibitory mechanism of the phenolic acid compounds in the model of dairy food was discussed by the trapping and scavenging of glyoxal. The results of this study exhibit that seven major antioxidant phenolic acid compounds may play important roles in the antioxidant activity and CML inhibition of the vinasse extract in a model of dairy foods.
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spelling pubmed-65148542019-05-30 Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food Wang, Yuzhen Liu, Huilin Zhang, Dianwei Liu, Jingmin Wang, Jing Wang, Shuo Sun, Baoguo Molecules Article The inhibitory effects of baijiu vinasse extract and its phenolic acid compounds on the N(ε)-carboxymethyllysine (CML) formation from dairy food were investigated. The inhibitory effect of the baijiu vinasse extract against CML formation was 43.2% in the casein and D-glucose model, which used 6 mL of the 70% acetone extract at 60 °C for 40 min. The HPLC-MS/MS profiles of the vinasse extract indicated that vanillic, chlorogenic, p-coumaric, sinapic, caffeic, ferulic, and syringic acids were seven major phenolic acid compounds. Furthermore, the inhibitory mechanism of the phenolic acid compounds in the model of dairy food was discussed by the trapping and scavenging of glyoxal. The results of this study exhibit that seven major antioxidant phenolic acid compounds may play important roles in the antioxidant activity and CML inhibition of the vinasse extract in a model of dairy foods. MDPI 2019-04-18 /pmc/articles/PMC6514854/ /pubmed/31003408 http://dx.doi.org/10.3390/molecules24081526 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Yuzhen
Liu, Huilin
Zhang, Dianwei
Liu, Jingmin
Wang, Jing
Wang, Shuo
Sun, Baoguo
Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food
title Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food
title_full Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food
title_fullStr Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food
title_full_unstemmed Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food
title_short Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of N(ε)-Carboxymethyllysine in Dairy Food
title_sort baijiu vinasse extract scavenges glyoxal and inhibits the formation of n(ε)-carboxymethyllysine in dairy food
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514854/
https://www.ncbi.nlm.nih.gov/pubmed/31003408
http://dx.doi.org/10.3390/molecules24081526
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