Cargando…
PMN-MDSCs Enhance CTC Metastatic Properties through Reciprocal Interactions via ROS/Notch/Nodal Signaling
Intratumoral infiltration of myeloid-derived suppressor cells (MDSCs) is known to promote neoplastic growth by inhibiting the tumoricidal activity of T cells. However, direct interactions between patient-derived MDSCs and circulating tumors cells (CTCs) within the microenvironment of blood remain un...
Autores principales: | Sprouse, Marc L., Welte, Thomas, Boral, Debasish, Liu, Haowen N., Yin, Wei, Vishnoi, Monika, Goswami-Sewell, Debalina, Li, Lili, Pei, Guangsheng, Jia, Peilin, Glitza-Oliva, Isabella C., Marchetti, Dario |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514876/ https://www.ncbi.nlm.nih.gov/pubmed/31003475 http://dx.doi.org/10.3390/ijms20081916 |
Ejemplares similares
-
The identification of a TNBC liver metastasis gene signature by sequential CTC‐xenograft modeling
por: Vishnoi, Monika, et al.
Publicado: (2019) -
Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs
por: Mastio, Jérôme, et al.
Publicado: (2019) -
mTOR Signaling Regulates the Development and Therapeutic Efficacy of PMN-MDSCs in Acute GVHD
por: Li, Xiaoqing, et al.
Publicado: (2021) -
Molecular characterization of breast cancer CTCs associated with brain metastasis
por: Boral, Debasish, et al.
Publicado: (2017) -
Temporal and spatial profile of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) in ischemic stroke in mice
por: Kawano, Tomohiro, et al.
Publicado: (2019)