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Identification of ADAM12 as a Novel Basigin Sheddase
The transmembrane glycoprotein basigin, a member of the immunoglobulin superfamily, stimulates matrix metalloproteinase (MMP)-mediated extracellular matrix (ECM) degradation and thereby drives cancer cell invasion. Basigin is proteolytically shed from the cell surface and high concentrations of solu...
Autores principales: | Albrechtsen, Reidar, Albrechtsen, Nicolai J. Wewer, Gnosa, Sebastian, Schwarz, Jeanette, Dyrskjøt, Lars, Kveiborg, Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514901/ https://www.ncbi.nlm.nih.gov/pubmed/31013576 http://dx.doi.org/10.3390/ijms20081957 |
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