Regional Variation in Comorbid Prediabetes and Diabetes and Associated Factors among Hypertensive Individuals in Rural Bangladesh, Pakistan, and Sri Lanka

We aimed to explore the cross-country variation in the prevalence of comorbid prediabetes or diabetes and determine the sociodemographic, lifestyle, and clinical factors, especially body mass index (BMI) and waist circumference, associated with comorbid diabetes in individuals with hypertension in r...

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Autores principales: Feng, Liang, Naheed, Aliya, de Silva, H. Asita, Jehan, Imtiaz, Raqib, Rubhana, Islam, Md Tauhidul, Luke, Nathasha, Kasturiratne, Anuradhani, Farazdaq, Hamida, Senan, Sahar, Jafar, Tazeen H., COBRA-BPS Study Group
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515018/
https://www.ncbi.nlm.nih.gov/pubmed/31183214
http://dx.doi.org/10.1155/2019/4914158
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author Feng, Liang
Naheed, Aliya
de Silva, H. Asita
Jehan, Imtiaz
Raqib, Rubhana
Islam, Md Tauhidul
Luke, Nathasha
Kasturiratne, Anuradhani
Farazdaq, Hamida
Senan, Sahar
Jafar, Tazeen H.
COBRA-BPS Study Group,
author_facet Feng, Liang
Naheed, Aliya
de Silva, H. Asita
Jehan, Imtiaz
Raqib, Rubhana
Islam, Md Tauhidul
Luke, Nathasha
Kasturiratne, Anuradhani
Farazdaq, Hamida
Senan, Sahar
Jafar, Tazeen H.
COBRA-BPS Study Group,
author_sort Feng, Liang
collection PubMed
description We aimed to explore the cross-country variation in the prevalence of comorbid prediabetes or diabetes and determine the sociodemographic, lifestyle, and clinical factors, especially body mass index (BMI) and waist circumference, associated with comorbid diabetes in individuals with hypertension in rural South Asia. We analyzed cross-sectional data of 2426 hypertensive individuals of ≥40 years from 30 randomly selected rural communities in Bangladesh, Pakistan, and Sri Lanka. Prediabetes was defined as fasting plasma glucose (FPG) between 100 and 125 mg/dL without use of antidiabetic treatment and diabetes as FPG ≥126 mg/dL or use of antidiabetic medication. The prevalence (95% CI) of prediabetes or diabetes (53.5% (51.5%, 55.5%)) and diabetes (27.7% (25.9%, 29.5%)) was high in the overall hypertensive study population in rural communities in 3 countries. Rural communities in Sri Lanka had the highest crude prevalence of prediabetes or diabetes and diabetes (73.1% and 39.3%) with hypertension, followed by those in Bangladesh (47.4% and 23.1%) and Pakistan (39.2% and 20.5%). The factors independently associated with comorbid diabetes and hypertension were residing in rural communities in Sri Lanka, higher education, international wealth index, waist circumference, pulse pressure, triglyceride, and lower high-density lipoprotein. The association of diabetes with waist circumference was stronger than with BMI in hypertensive individuals. Prediabetes or diabetes are alarmingly common among adults with hypertension and vary among countries in rural South Asia. The high prevalence of comorbid diabetes in Sri Lanka among hypertensives is not fully explained by conventional risk factors and needs further etiological research. Urgent public health efforts are needed to integrate diabetes control within hypertension management programs in rural South Asia, including screening waist circumference.
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spelling pubmed-65150182019-06-10 Regional Variation in Comorbid Prediabetes and Diabetes and Associated Factors among Hypertensive Individuals in Rural Bangladesh, Pakistan, and Sri Lanka Feng, Liang Naheed, Aliya de Silva, H. Asita Jehan, Imtiaz Raqib, Rubhana Islam, Md Tauhidul Luke, Nathasha Kasturiratne, Anuradhani Farazdaq, Hamida Senan, Sahar Jafar, Tazeen H. COBRA-BPS Study Group, J Obes Research Article We aimed to explore the cross-country variation in the prevalence of comorbid prediabetes or diabetes and determine the sociodemographic, lifestyle, and clinical factors, especially body mass index (BMI) and waist circumference, associated with comorbid diabetes in individuals with hypertension in rural South Asia. We analyzed cross-sectional data of 2426 hypertensive individuals of ≥40 years from 30 randomly selected rural communities in Bangladesh, Pakistan, and Sri Lanka. Prediabetes was defined as fasting plasma glucose (FPG) between 100 and 125 mg/dL without use of antidiabetic treatment and diabetes as FPG ≥126 mg/dL or use of antidiabetic medication. The prevalence (95% CI) of prediabetes or diabetes (53.5% (51.5%, 55.5%)) and diabetes (27.7% (25.9%, 29.5%)) was high in the overall hypertensive study population in rural communities in 3 countries. Rural communities in Sri Lanka had the highest crude prevalence of prediabetes or diabetes and diabetes (73.1% and 39.3%) with hypertension, followed by those in Bangladesh (47.4% and 23.1%) and Pakistan (39.2% and 20.5%). The factors independently associated with comorbid diabetes and hypertension were residing in rural communities in Sri Lanka, higher education, international wealth index, waist circumference, pulse pressure, triglyceride, and lower high-density lipoprotein. The association of diabetes with waist circumference was stronger than with BMI in hypertensive individuals. Prediabetes or diabetes are alarmingly common among adults with hypertension and vary among countries in rural South Asia. The high prevalence of comorbid diabetes in Sri Lanka among hypertensives is not fully explained by conventional risk factors and needs further etiological research. Urgent public health efforts are needed to integrate diabetes control within hypertension management programs in rural South Asia, including screening waist circumference. Hindawi 2019-04-30 /pmc/articles/PMC6515018/ /pubmed/31183214 http://dx.doi.org/10.1155/2019/4914158 Text en Copyright © 2019 Liang Feng et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Feng, Liang
Naheed, Aliya
de Silva, H. Asita
Jehan, Imtiaz
Raqib, Rubhana
Islam, Md Tauhidul
Luke, Nathasha
Kasturiratne, Anuradhani
Farazdaq, Hamida
Senan, Sahar
Jafar, Tazeen H.
COBRA-BPS Study Group,
Regional Variation in Comorbid Prediabetes and Diabetes and Associated Factors among Hypertensive Individuals in Rural Bangladesh, Pakistan, and Sri Lanka
title Regional Variation in Comorbid Prediabetes and Diabetes and Associated Factors among Hypertensive Individuals in Rural Bangladesh, Pakistan, and Sri Lanka
title_full Regional Variation in Comorbid Prediabetes and Diabetes and Associated Factors among Hypertensive Individuals in Rural Bangladesh, Pakistan, and Sri Lanka
title_fullStr Regional Variation in Comorbid Prediabetes and Diabetes and Associated Factors among Hypertensive Individuals in Rural Bangladesh, Pakistan, and Sri Lanka
title_full_unstemmed Regional Variation in Comorbid Prediabetes and Diabetes and Associated Factors among Hypertensive Individuals in Rural Bangladesh, Pakistan, and Sri Lanka
title_short Regional Variation in Comorbid Prediabetes and Diabetes and Associated Factors among Hypertensive Individuals in Rural Bangladesh, Pakistan, and Sri Lanka
title_sort regional variation in comorbid prediabetes and diabetes and associated factors among hypertensive individuals in rural bangladesh, pakistan, and sri lanka
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515018/
https://www.ncbi.nlm.nih.gov/pubmed/31183214
http://dx.doi.org/10.1155/2019/4914158
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