Silibinin Downregulates the NF-κB Pathway and NLRP1/NLRP3 Inflammasomes in Monocytes from Pregnant Women with Preeclampsia

Preeclampsia (PE) is a human pregnancy-specific syndrome with abnormal activation of cells from the innate immune system. The present study evaluated whether silibinin (SB) treatment of monocytes from preeclamptic women could modulate NLRP1 and NLRP3 inflammasomes as well as TLR4/NF-κB pathway activ...

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Detalles Bibliográficos
Autores principales: Matias, Mariana Leticia, Gomes, Virginia Juliani, Romao-Veiga, Mariana, Ribeiro, Vanessa Rocha, Nunes, Priscila Rezeck, Romagnoli, Graziela Gorete, Peracoli, Jose Carlos, Peracoli, Maria Terezinha Serrao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515043/
https://www.ncbi.nlm.nih.gov/pubmed/31010153
http://dx.doi.org/10.3390/molecules24081548

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