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Genome-wide DNA methylation encodes cardiac transcriptional reprogramming in human ischemic heart failure
Ischemic cardiomyopathy (ICM) is the clinical endpoint of coronary heart disease and a leading cause of heart failure. Despite growing demands to develop personalized approaches to treat ICM, progress is limited by inadequate knowledge of its pathogenesis. Since epigenetics has been implicated in th...
Autores principales: | Pepin, Mark E., Ha, Chae-Myeong, Crossman, David K., Litovsky, Silvio H., Varambally, Sooryanarayana, Barchue, Joseph P., Pamboukian, Salpy V., Diakos, Nikolaos A., Drakos, Stavros G., Pogwizd, Steven M., Wende, Adam R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515060/ https://www.ncbi.nlm.nih.gov/pubmed/30089854 http://dx.doi.org/10.1038/s41374-018-0104-x |
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