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Antitumor effects of flavopiridol, a cyclin-dependent kinase inhibitor, on human cholangiocarcinoma in vitro and in an in vivo xenograft model

Flavopiridol, a pan-cyclin-dependent kinase (CDK) inhibitor, was recently identified as an effective antitumor agent for several cancers. We investigated the antitumor effect of flavopiridol on cholangiocarcinoma (CCA), in vitro and in vivo. A methylthiotetrazole assay revealed that the proliferatio...

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Detalles Bibliográficos
Autores principales:	Saisomboon, Saowaluk, Kariya, Ryusho, Vaeteewoottacharn, Kulthida, Wongkham, Sopit, Sawanyawisuth, Kanlayanee, Okada, Seiji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515137/ https://www.ncbi.nlm.nih.gov/pubmed/31193061 http://dx.doi.org/10.1016/j.heliyon.2019.e01675

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