Previously reported placebo-response-associated variants do not predict patient outcomes in inflammatory disease Phase III trial placebo arms

In clinical trials, a placebo response refers to improvement in disease symptoms arising from the psychological effect of receiving a treatment rather than the actual treatment under investigation. Previous research has reported genomic variation associated with the likelihood of observing a placebo...

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Detalles Bibliográficos
Autores principales: Haug-Baltzell, Asher, Bhangale, Tushar R., Chang, Diana, Dressen, Amy, Yaspan, Brian L., Ortmann, Ward, Brauer, Matthew J., Hunkapiller, Julie, Reeder, Jens, Mukhyala, Kiran, Cuenco, Karen T., Tom, Jennifer A., Cowgill, Amy, Vogel, Jan, Forrest, William F., Behrens, Timothy W., Graham, Robert R., Wuster, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515143/
https://www.ncbi.nlm.nih.gov/pubmed/29550837
http://dx.doi.org/10.1038/s41435-018-0018-z

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