TRPV1 Induced Apoptosis of Colorectal Cancer Cells by Activating Calcineurin-NFAT2-p53 Signaling Pathway

BACKGROUND/AIMS: TRPV1 is a nonselective Ca(2+) channel which has recently been observed in many cancers, while its effect on cell proliferation, apoptosis, metabolism, and cancer development in colorectal cancer (CRC) is still unclear. In this study, we hypothesized that TRPV1 is a tumor suppressor...

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Detalles Bibliográficos
Autores principales: Hou, Nengyi, He, Xuelai, Yang, Yuhui, Fu, Junwen, Zhang, Wei, Guo, Zhiyi, Hu, Yang, Liang, Liqin, Xie, Wei, Xiong, Haibo, Wang, Kang, Pang, Minghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515190/
https://www.ncbi.nlm.nih.gov/pubmed/31183372
http://dx.doi.org/10.1155/2019/6712536

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