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Menaquinone-4 Amplified Glucose-Stimulated Insulin Secretion in Isolated Mouse Pancreatic Islets and INS-1 Rat Insulinoma Cells
Vitamin K2 is indispensable for blood coagulation and bone metabolism. Menaquinone-4 (MK-4) is the predominant homolog of vitamin K2, which is present in large amounts in the pancreas, although its function is unclear. Meanwhile, β-cell dysfunction following insulin secretion has been found to decre...
Autores principales: | Ho, Hsin-Jung, Shirakawa, Hitoshi, Hirahara, Keisukei, Sone, Hideyuki, Kamiyama, Shin, Komai, Michio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515216/ https://www.ncbi.nlm.nih.gov/pubmed/31018587 http://dx.doi.org/10.3390/ijms20081995 |
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