Cargando…
Improving the Utility of the Tox21 Dataset by Deep Metadata Annotations and Constructing Reusable Benchmarked Chemical Reference Signatures
The Toxicology in the 21st Century (Tox21) project seeks to develop and test methods for high-throughput examination of the effect certain chemical compounds have on biological systems. Although primary and toxicity assay data were readily available for multiple reporter gene modified cell lines, ex...
Autores principales: | Cooper, Daniel J., Schürer, Stephan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515292/ https://www.ncbi.nlm.nih.gov/pubmed/31018579 http://dx.doi.org/10.3390/molecules24081604 |
Ejemplares similares
-
Structure–activity relationship-based chemical classification of highly imbalanced Tox21 datasets
por: Idakwo, Gabriel, et al.
Publicado: (2020) -
Profiling the Tox21 Chemical Collection for Acetylcholinesterase Inhibition
por: Li, Shuaizhang, et al.
Publicado: (2021) -
Bioactivity Signatures of Drugs vs. Environmental Chemicals Revealed by Tox21 High-Throughput Screening Assays
por: Ngan, Deborah K., et al.
Publicado: (2019) -
Maximizing the reusability of gene expression data by predicting missing metadata
por: Lung, Pei-Yau, et al.
Publicado: (2020) -
Tox21Enricher-Shiny: an R Shiny application for toxicity functional annotation analysis
por: Combs, Parker, et al.
Publicado: (2023)