Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment

Tumor-associated macrophages are an abundant cell type in the tumor microenvironment. These macrophages serve as a promising target for treatment of cancer due to their roles in promoting cancer progression and simultaneous immunosuppression. The TAM receptors (Tyro3, Axl and MerTK) are promising th...

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Detalles Bibliográficos
Autores principales: Myers, Kayla V., Amend, Sarah R., Pienta, Kenneth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515593/
https://www.ncbi.nlm.nih.gov/pubmed/31088471
http://dx.doi.org/10.1186/s12943-019-1022-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515593/
https://www.ncbi.nlm.nih.gov/pubmed/31088471
http://dx.doi.org/10.1186/s12943-019-1022-2

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