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High Body Mass Index is Associated with Elevated Blood Levels of Progerin mRNA

Obesity is a well-described risk factor resulting in premature aging of the cardiovascular system ultimately limiting longevity. Premature cardiac death and aging is the hallmark of Hutchinson–Gilford syndrome (HGPS), a disease caused by defined mutations in the lamin A gene leading to a shortened p...

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Detalles Bibliográficos
Autores principales: Messner, Moritz, Ghadge, Santhosh Kumar, Schuetz, Thomas, Seiringer, Herbert, Pölzl, Gerhard, Zaruba, Marc-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515652/
https://www.ncbi.nlm.nih.gov/pubmed/31018503
http://dx.doi.org/10.3390/ijms20081976

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