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RVG-modified exosomes derived from mesenchymal stem cells rescue memory deficits by regulating inflammatory responses in a mouse model of Alzheimer’s disease

BACKGROUND: Exosomes are lipid-bilayer enclosed nano-sized vesicles that transfer functional cellular proteins, mRNA and miRNAs. Mesenchymal stem cells (MSCs) derived exosomes have been demonstrated to prevent memory deficits in the animal model of Alzheimer’s disease (AD). However, the intravenousl...

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Detalles Bibliográficos
Autores principales:	Cui, Guo-hong, Guo, Hai-dong, Li, Han, Zhai, Yu, Gong, Zhang-bin, Wu, Jing, Liu, Jian-sheng, Dong, You-rong, Hou, Shuang-xing, Liu, Jian-ren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515654/ https://www.ncbi.nlm.nih.gov/pubmed/31114624 http://dx.doi.org/10.1186/s12979-019-0150-2

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