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Negative regulation of glial Tim‐3 inhibits the secretion of inflammatory factors and modulates microglia to antiinflammatory phenotype after experimental intracerebral hemorrhage in rats

AIMS: To investigate the critical role of Tim‐3 in the polarization of microglia in intracerebral hemorrhage (ICH)‐induced secondary brain injury (SBI). METHODS: An in vivo ICH model was established by autologous whole blood injection into the right basal ganglia in rats. The primary cultured microg...

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Detalles Bibliográficos
Autores principales:	Chen, Zhou‐Qing, Yu, Hao, Li, Hai‐Ying, Shen, Hai‐Tao, Li, Xiang, Zhang, Ju‐Yi, Zhang, Zhu‐Wei, Wang, Zhong, Chen, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515709/ https://www.ncbi.nlm.nih.gov/pubmed/30677253 http://dx.doi.org/10.1111/cns.13100

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