Propofol improved hypoxia‐impaired integrity of blood‐brain barrier via modulating the expression and phosphorylation of zonula occludens‐1

AIMS: Hypoxia may damage blood‐brain barrier (BBB). The neuroprotective effect of propofol has been reported. We aimed to identify whether and how propofol improved hypoxia‐induced impairment of BBB integrity. METHODS: Mouse brain microvascular endothelial cells (MBMECs) and astrocytes were cocultur...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Ju, Xing‐Zhu, Lu, Yan, Ding, Xiao‐Wei, Miao, Chang‐Hong, Chen, Jia‐Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515893/
https://www.ncbi.nlm.nih.gov/pubmed/30680941
http://dx.doi.org/10.1111/cns.13101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515893/
https://www.ncbi.nlm.nih.gov/pubmed/30680941
http://dx.doi.org/10.1111/cns.13101

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