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Propofol improved hypoxia‐impaired integrity of blood‐brain barrier via modulating the expression and phosphorylation of zonula occludens‐1
AIMS: Hypoxia may damage blood‐brain barrier (BBB). The neuroprotective effect of propofol has been reported. We aimed to identify whether and how propofol improved hypoxia‐induced impairment of BBB integrity. METHODS: Mouse brain microvascular endothelial cells (MBMECs) and astrocytes were cocultur...
Autores principales: | Chen, Wei, Ju, Xing‐Zhu, Lu, Yan, Ding, Xiao‐Wei, Miao, Chang‐Hong, Chen, Jia‐Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515893/ https://www.ncbi.nlm.nih.gov/pubmed/30680941 http://dx.doi.org/10.1111/cns.13101 |
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