Cargando…

Down Regulation of the Expression of ELMO3 by COX2 Inhibitor Suppresses Tumor Growth and Metastasis in Non-Small-Cell Lung Cancer

Non-small cell lung cancer (NSCLC) is one of the most common malignancies. Studies have shown that engulfment and cell motility 3 (ELMO3) is highly expressed in NSCLC and can be used as a novel biomarker, but its underlying mechanism remains to be explored. The aim of this study was to investigate t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Cailong, Zhang, Yong, Meng, Qinghai, Dai, Guoliang, Jiang, Zhitao, Bao, Hongguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515945/ https://www.ncbi.nlm.nih.gov/pubmed/31134158 http://dx.doi.org/10.3389/fonc.2019.00363

Ejemplares similares

Knockdown of ELMO3 Suppresses Growth, Invasion and Metastasis of Colorectal Cancer
por: Peng, Hui-Yun, et al.
Publicado: (2016)

Suppression of the RAC1/MLK3/p38 Signaling Pathway by β-Elemene Alleviates Sepsis-Associated Encephalopathy in Mice
por: Pan, Cailong, et al.
Publicado: (2019)

NSCLC metastasis: going with ELMO3
por: Goyette, Marie-Anne, et al.
Publicado: (2014)

Comparative Morphological, Metabolic and Transcriptome Analyses in elmo1 ( −/− ), elmo2 ( −/− ), and elmo3 ( −/− ) Zebrafish Mutants Identified a Functional Non-Redundancy of the Elmo Proteins
por: Boger, Mike, et al.
Publicado: (2022)

Caffeic Acid Phenethyl Ester Prevents Colitis-Associated Cancer by Inhibiting NLRP3 Inflammasome
por: Dai, Guoliang, et al.
Publicado: (2020)

Silencing ELMO3 Inhibits the Growth, Invasion, and Metastasis of Gastric Cancer
por: Hu, Yan, et al.
Publicado: (2018)

Knock-down of ELMO1 in Paediatric Rhabdomyosarcoma Cells by Nanoparticle Mediated siRNA Delivery
por: Huang, Xinyue, et al.
Publicado: (2016)

ELMO: an innovative interface for noninvasive ventilation
por: Pinheiro, Bruno Valle, et al.
Publicado: (2022)

Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds
por: Weng, Zhuangfeng, et al.
Publicado: (2019)

pELMO, an optimised in-house cloning vector
por: Ramos, Andrea E., et al.
Publicado: (2017)

Golgi ELMO1 binds QUA1, QUA2, GAUT9, and ELMO4 and is required for pectin accumulation in Arabidopsis
por: Kohorn, Bruce D., et al.
Publicado: (2023)

Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis
por: Zhou, Ping, et al.
Publicado: (2017)

Down-Regulation of Collagen Hydroxylation in Colorectal Liver Metastasis
por: van Huizen, Nick A., et al.
Publicado: (2020)

ELMO2 association with Gαi2 regulates pancreatic cancer cell chemotaxis and metastasis
por: Wang, Yecheng, et al.
Publicado: (2020)

Correction to: Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis
por: Zhou, Ping, et al.
Publicado: (2021)

Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma
por: Liu, Qian, et al.
Publicado: (2021)

Retraction: Combination of Tanshinone IIA and Cisplatin Inhibits Esophageal Squamous Cell Carcinoma by Down-Regulating NF-kB/COX-2/VEGF Pathway
Publicado: (2021)

Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling
por: Guo, Wenjing, et al.
Publicado: (2020)

ELMO1: More Than Just a Director of Phagocytosis
por: McCormick, Beth A.
Publicado: (2015)

Intermolecular steric inhibition of Ephexin4 is relieved by Elmo1
por: Kim, Kwanhyeong, et al.
Publicado: (2017)

ELMO1 Deficiency Reduces Neutrophil Chemotaxis in Murine Peritonitis
por: Yu, Shuxiang, et al.
Publicado: (2023)

PA28α/β Promote Breast Cancer Cell Invasion and Metastasis via Down-Regulation of CDK15
por: Li, Shengnan, et al.
Publicado: (2019)

Mechanisms and Future of Non-Small Cell Lung Cancer Metastasis
por: Zhu, Tianhao, et al.
Publicado: (2020)

Retraction: Corrigendum: Tan IIA Combined With DDP Inhibits Esophageal Squamous Cell Carcinoma via Down-Regulating the NF-kB/COX-2/VEGF Pathway
Publicado: (2021)

Fibroblasts mediate the angiogenesis of pheochromocytoma by increasing COX4I2 expression
por: Mao, Yongxin, et al.
Publicado: (2022)

Prediction of bone metastasis in non-small cell lung cancer based on machine learning
por: Li, Meng-Pan, et al.
Publicado: (2023)

An ELMO2-RhoG-ILK network modulates microtubule dynamics
por: Jackson, Bradley C., et al.
Publicado: (2015)

ELMO1 Regulates RANKL-Stimulated Differentiation and Bone Resorption of Osteoclasts
por: Liang, Xinyue, et al.
Publicado: (2021)

ELMO1 signaling is a promoter of osteoclast function and bone loss
por: Arandjelovic, Sanja, et al.
Publicado: (2021)

Functional Verification of Novel ELMO1 Variants by Live Imaging in Zebrafish
por: Xue, Rongtao, et al.
Publicado: (2021)

Targeting Ras-binding domain of ELMO1 by computational nanobody design
por: Tam, Chunlai, et al.
Publicado: (2023)

Association between Gαi2 and ELMO1/Dock180 connects chemokine signalling with Rac activation and metastasis
por: Li, Hongyan, et al.
Publicado: (2013)

Osteosarcoma-Derived Small Extracellular Vesicles Enhance Tumor Metastasis and Suppress Osteoclastogenesis by miR-146a-5p
por: Araki, Yoshihiro, et al.
Publicado: (2021)

Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway
por: Shi, Shaomin, et al.
Publicado: (2021)

Elevated BCAA Suppresses the Development and Metastasis of Breast Cancer
por: Chi, Rui, et al.
Publicado: (2022)

An Adaptive Transfer-Learning-Based Deep Cox Neural Network for Hepatocellular Carcinoma Prognosis Prediction
por: Chai, Hua, et al.
Publicado: (2021)

The Therapeutic Effect and Clinical Outcome of Immune Checkpoint Inhibitors on Bone Metastasis in Advanced Non-Small-Cell Lung Cancer
por: Asano, Yohei, et al.
Publicado: (2022)

COX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs
por: Gurpinar, Evrim, et al.
Publicado: (2013)

MYCN mRNA degradation and cancer suppression by a selective small-molecule inhibitor in MYCN-amplified neuroblastoma
por: Liu, Tao, et al.
Publicado: (2022)

PARK2 Suppresses Proliferation and Tumorigenicity in Non-small Cell Lung Cancer
por: Duan, Huijie, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_m4vgjji6032bve2n8me3qih1c1