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Outcome Analysis of Posterolateral Decompression and Spinal Stabilization for Tuberculous Spine

AIM: This is a prospective study to analyze the clinical, radiological, and functional outcomes of posterolateral decompression and spinal stabilization with pedicle screws and rods done for the thoracolumbar tuberculous spine. MATERIALS AND METHODS: This study was conducted at Gandhi Medical Colleg...

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Autores principales: Musali, Siddartha Reddy, Gollapudi, Prakash Rao, Manne, Srikrishnaaditya, Butkuri, Nagarjuna, Kumar, Thatikonda Satish, Kotha, Vamshi Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515998/
https://www.ncbi.nlm.nih.gov/pubmed/31143265
http://dx.doi.org/10.4103/ajns.AJNS_274_18
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author Musali, Siddartha Reddy
Gollapudi, Prakash Rao
Manne, Srikrishnaaditya
Butkuri, Nagarjuna
Kumar, Thatikonda Satish
Kotha, Vamshi Krishna
author_facet Musali, Siddartha Reddy
Gollapudi, Prakash Rao
Manne, Srikrishnaaditya
Butkuri, Nagarjuna
Kumar, Thatikonda Satish
Kotha, Vamshi Krishna
author_sort Musali, Siddartha Reddy
collection PubMed
description AIM: This is a prospective study to analyze the clinical, radiological, and functional outcomes of posterolateral decompression and spinal stabilization with pedicle screws and rods done for the thoracolumbar tuberculous spine. MATERIALS AND METHODS: This study was conducted at Gandhi Medical College and Hospital from September 2016 to September 2017 on 30 patients who underwent posterolateral decompression and spinal stabilization using pedicle screw and rod fixation for active spinal tuberculosis. Pain, erythrocyte sedimentation rate (ESR), kyphotic angle correction, and Frankel's grading were taken to study the clinical, radiological, and functional outcome at the end of 1 year. Other parameters taken into consideration were the duration of stay and level of involvement; antituberculous therapy was given to all the patients for 16–18 months until the signs of radiological healing were evident. RESULTS: This study comprised of 30 patients with a mean age of presentation of 39.835 ± 14.75 and M: F ratio of 1:1. The mean duration of stay is 10.67 ± 4.06, and the most common level of involvement is D6–D11. Kyphotic angle was corrected by a mean of 19.08 ± 5.44 at the end of 1 year (P < 0.001). Visual analog score improved from a median of 8 preoperatively to 2 at follow-up (P < 0.001). ESR improved from a mean of 37.08 ± 12.64 mm/h preoperatively to 19.83 ± 13.68 mm/h at follow-up (P = 0.01). There was an improvement in Frankel's grading in most of the patients at the end of 12 months. Radiological healing was evident in the form of the reappearance of trabeculae formation and bony fusion at the end of 12 months. CONCLUSION: Posterolateral approach is a good method for decompression and spinal stabilization because of significant kyphotic correction, improvement in pain, good neurological recovery, less duration of stay, and less morbidity.
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spelling pubmed-65159982019-05-29 Outcome Analysis of Posterolateral Decompression and Spinal Stabilization for Tuberculous Spine Musali, Siddartha Reddy Gollapudi, Prakash Rao Manne, Srikrishnaaditya Butkuri, Nagarjuna Kumar, Thatikonda Satish Kotha, Vamshi Krishna Asian J Neurosurg Original Article AIM: This is a prospective study to analyze the clinical, radiological, and functional outcomes of posterolateral decompression and spinal stabilization with pedicle screws and rods done for the thoracolumbar tuberculous spine. MATERIALS AND METHODS: This study was conducted at Gandhi Medical College and Hospital from September 2016 to September 2017 on 30 patients who underwent posterolateral decompression and spinal stabilization using pedicle screw and rod fixation for active spinal tuberculosis. Pain, erythrocyte sedimentation rate (ESR), kyphotic angle correction, and Frankel's grading were taken to study the clinical, radiological, and functional outcome at the end of 1 year. Other parameters taken into consideration were the duration of stay and level of involvement; antituberculous therapy was given to all the patients for 16–18 months until the signs of radiological healing were evident. RESULTS: This study comprised of 30 patients with a mean age of presentation of 39.835 ± 14.75 and M: F ratio of 1:1. The mean duration of stay is 10.67 ± 4.06, and the most common level of involvement is D6–D11. Kyphotic angle was corrected by a mean of 19.08 ± 5.44 at the end of 1 year (P < 0.001). Visual analog score improved from a median of 8 preoperatively to 2 at follow-up (P < 0.001). ESR improved from a mean of 37.08 ± 12.64 mm/h preoperatively to 19.83 ± 13.68 mm/h at follow-up (P = 0.01). There was an improvement in Frankel's grading in most of the patients at the end of 12 months. Radiological healing was evident in the form of the reappearance of trabeculae formation and bony fusion at the end of 12 months. CONCLUSION: Posterolateral approach is a good method for decompression and spinal stabilization because of significant kyphotic correction, improvement in pain, good neurological recovery, less duration of stay, and less morbidity. Medknow Publications & Media Pvt Ltd 2019 /pmc/articles/PMC6515998/ /pubmed/31143265 http://dx.doi.org/10.4103/ajns.AJNS_274_18 Text en Copyright: © 2019 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Musali, Siddartha Reddy
Gollapudi, Prakash Rao
Manne, Srikrishnaaditya
Butkuri, Nagarjuna
Kumar, Thatikonda Satish
Kotha, Vamshi Krishna
Outcome Analysis of Posterolateral Decompression and Spinal Stabilization for Tuberculous Spine
title Outcome Analysis of Posterolateral Decompression and Spinal Stabilization for Tuberculous Spine
title_full Outcome Analysis of Posterolateral Decompression and Spinal Stabilization for Tuberculous Spine
title_fullStr Outcome Analysis of Posterolateral Decompression and Spinal Stabilization for Tuberculous Spine
title_full_unstemmed Outcome Analysis of Posterolateral Decompression and Spinal Stabilization for Tuberculous Spine
title_short Outcome Analysis of Posterolateral Decompression and Spinal Stabilization for Tuberculous Spine
title_sort outcome analysis of posterolateral decompression and spinal stabilization for tuberculous spine
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515998/
https://www.ncbi.nlm.nih.gov/pubmed/31143265
http://dx.doi.org/10.4103/ajns.AJNS_274_18
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