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Meningiomas with Collagenous Rosettes: A Report of Three Cases

Formation of rosettes is very rarely encountered in meningiomas. The 2016 WHO classification of central nervous system tumors mentions it as a rare pattern secondarily encountered in different variants. We report three cases of meningiomas forming collagenous rosettes. Case 1 was a 60-year-old male...

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Autores principales: Vaidya, Mihir Mohan, Shenoy, Asha Sharad, Goel, Naina Atul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516015/
https://www.ncbi.nlm.nih.gov/pubmed/31143285
http://dx.doi.org/10.4103/ajns.AJNS_256_18
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author Vaidya, Mihir Mohan
Shenoy, Asha Sharad
Goel, Naina Atul
author_facet Vaidya, Mihir Mohan
Shenoy, Asha Sharad
Goel, Naina Atul
author_sort Vaidya, Mihir Mohan
collection PubMed
description Formation of rosettes is very rarely encountered in meningiomas. The 2016 WHO classification of central nervous system tumors mentions it as a rare pattern secondarily encountered in different variants. We report three cases of meningiomas forming collagenous rosettes. Case 1 was a 60-year-old male with a right frontoparietal mass lesion. Excisional biopsy showed features of atypical meningioma (WHO Grade II) with diffusely scattered collagenous rosettes. Case 2 was a 48-year-old male with right frontoparietal space-occupying lesion. Microscopy revealed a papillary variant of meningioma (WHO Grade III) with prominent diffusely scattered collagenous rosettes. Case 3 was a 75-year-old female with left parietal convexity tumor. Microscopy revealed a clear-cell meningioma (WHO Grade II) with cerebral invasion. Focal collagenous rosettes and fibrosclerotic whorls were noted. In all three cases, Masson's trichrome was used to confirm collagenous nature of the rosettes. All three tumors were positive for epithelial membrane antigen and vimentin.
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spelling pubmed-65160152019-05-29 Meningiomas with Collagenous Rosettes: A Report of Three Cases Vaidya, Mihir Mohan Shenoy, Asha Sharad Goel, Naina Atul Asian J Neurosurg Case Report Formation of rosettes is very rarely encountered in meningiomas. The 2016 WHO classification of central nervous system tumors mentions it as a rare pattern secondarily encountered in different variants. We report three cases of meningiomas forming collagenous rosettes. Case 1 was a 60-year-old male with a right frontoparietal mass lesion. Excisional biopsy showed features of atypical meningioma (WHO Grade II) with diffusely scattered collagenous rosettes. Case 2 was a 48-year-old male with right frontoparietal space-occupying lesion. Microscopy revealed a papillary variant of meningioma (WHO Grade III) with prominent diffusely scattered collagenous rosettes. Case 3 was a 75-year-old female with left parietal convexity tumor. Microscopy revealed a clear-cell meningioma (WHO Grade II) with cerebral invasion. Focal collagenous rosettes and fibrosclerotic whorls were noted. In all three cases, Masson's trichrome was used to confirm collagenous nature of the rosettes. All three tumors were positive for epithelial membrane antigen and vimentin. Medknow Publications & Media Pvt Ltd 2019 /pmc/articles/PMC6516015/ /pubmed/31143285 http://dx.doi.org/10.4103/ajns.AJNS_256_18 Text en Copyright: © 2019 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Vaidya, Mihir Mohan
Shenoy, Asha Sharad
Goel, Naina Atul
Meningiomas with Collagenous Rosettes: A Report of Three Cases
title Meningiomas with Collagenous Rosettes: A Report of Three Cases
title_full Meningiomas with Collagenous Rosettes: A Report of Three Cases
title_fullStr Meningiomas with Collagenous Rosettes: A Report of Three Cases
title_full_unstemmed Meningiomas with Collagenous Rosettes: A Report of Three Cases
title_short Meningiomas with Collagenous Rosettes: A Report of Three Cases
title_sort meningiomas with collagenous rosettes: a report of three cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516015/
https://www.ncbi.nlm.nih.gov/pubmed/31143285
http://dx.doi.org/10.4103/ajns.AJNS_256_18
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