Vascular smooth muscle cell‐specific progerin expression in a mouse model of Hutchinson–Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite

Vascular stiffness is a major cause of cardiovascular disease during normal aging and in Hutchinson–Gilford progeria syndrome (HGPS), a rare genetic disorder caused by ubiquitous progerin expression. This mutant form of lamin A causes premature aging associated with cardiovascular alterations that l...

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Detalles Bibliográficos
Autores principales: del Campo, Lara, Sánchez‐López, Amanda, Salaices, Mercedes, von Kleeck, Ryan A., Expósito, Elba, González‐Gómez, Cristina, Cussó, Lorena, Guzmán‐Martínez, Gabriela, Ruiz‐Cabello, Jesús, Desco, Manuel, Assoian, Richard K., Briones, Ana M., Andrés, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516150/
https://www.ncbi.nlm.nih.gov/pubmed/30884114
http://dx.doi.org/10.1111/acel.12936

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