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Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction

Cardiovascular disease is the leading cause of death in individuals over 60 years old. Aging is associated with an increased prevalence of coronary artery disease and a poorer prognosis following acute myocardial infarction (MI). With age, senescent cells accumulate in tissues, including the heart,...

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Detalles Bibliográficos
Autores principales: Walaszczyk, Anna, Dookun, Emily, Redgrave, Rachael, Tual‐Chalot, Simon, Victorelli, Stella, Spyridopoulos, Ioakim, Owens, Andrew, Arthur, Helen M., Passos, João F., Richardson, Gavin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516151/
https://www.ncbi.nlm.nih.gov/pubmed/30920115
http://dx.doi.org/10.1111/acel.12945