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Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction
Cardiovascular disease is the leading cause of death in individuals over 60 years old. Aging is associated with an increased prevalence of coronary artery disease and a poorer prognosis following acute myocardial infarction (MI). With age, senescent cells accumulate in tissues, including the heart,...
Autores principales: | Walaszczyk, Anna, Dookun, Emily, Redgrave, Rachael, Tual‐Chalot, Simon, Victorelli, Stella, Spyridopoulos, Ioakim, Owens, Andrew, Arthur, Helen M., Passos, João F., Richardson, Gavin D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516151/ https://www.ncbi.nlm.nih.gov/pubmed/30920115 http://dx.doi.org/10.1111/acel.12945 |
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