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Decoy fitness peaks, tumor suppression, and aging
Recent reports by Martincorena et al and Yokoyama et al reveal unanticipated dynamics of somatic evolution in the esophageal epithelium, with clonal expansions apparently driven by mutations in Notch1 dominating the epithelium even in middle‐aged individuals, far outpacing the prevalence of these mu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516171/ https://www.ncbi.nlm.nih.gov/pubmed/30848555 http://dx.doi.org/10.1111/acel.12938 |