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1,25‐Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2‐antioxidant signaling and inactivation of p16/p53‐senescence signaling

We tested the hypothesis that 1,25‐dihydroxyvitamin D(3)[1α,25(OH)(2)D(3)] has antiaging effects via upregulating nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2), reducing reactive oxygen species (ROS), decreasing DNA damage, reducing p16/Rb and p53/p21 signaling, increasing cell proliferation, a...

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Detalles Bibliográficos
Autores principales:	Chen, Lulu, Yang, Renlei, Qiao, Wanxin, Zhang, Wei, Chen, Jie, Mao, Li, Goltzman, David, Miao, Dengshun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516172/ https://www.ncbi.nlm.nih.gov/pubmed/30907059 http://dx.doi.org/10.1111/acel.12951

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