Tendinosis develops from age‐ and oxygen tension‐dependent modulation of Rac1 activity

Age‐related tendon degeneration (tendinosis) is characterized by a phenotypic change in which tenocytes display characteristics of fibrochondrocytes and mineralized fibrochondrocytes. As tendon degeneration has been noted in vivo in areas of decreased tendon vascularity, we hypothesized that hypoxia...

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Detalles Bibliográficos
Autores principales: McBeath, Rowena, Edwards, Richard W., O’Hara, Brian J., Maltenfort, Mitchell G., Parks, Susan M., Steplewski, Andrzej, Osterman, A. Lee, Shapiro, Irving M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516173/
https://www.ncbi.nlm.nih.gov/pubmed/30938056
http://dx.doi.org/10.1111/acel.12934

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