KIN‐4/MAST kinase promotes PTEN‐mediated longevity of Caenorhabditis elegans via binding through a PDZ domain

PDZ domain‐containing proteins (PDZ proteins) act as scaffolds for protein–protein interactions and are crucial for a variety of signal transduction processes. However, the role of PDZ proteins in organismal lifespan and aging remains poorly understood. Here, we demonstrate that KIN‐4, a PDZ domain‐...

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Detalles Bibliográficos
Autores principales: An, Seon Woo A., Choi, Eun‐Seok, Hwang, Wooseon, Son, Heehwa G., Yang, Jae‐Seong, Seo, Keunhee, Nam, Hyun‐Jun, Nguyen, Nhung T. H., Kim, Eun Ji E., Suh, Bo Kyoung, Kim, Youngran, Nakano, Shunji, Ryu, Youngjae, Man Ha, Chang, Mori, Ikue, Park, Sang Ki, Yoo, Joo‐Yeon, Kim, Sanguk, Lee, Seung‐Jae V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516182/
https://www.ncbi.nlm.nih.gov/pubmed/30773781
http://dx.doi.org/10.1111/acel.12906

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