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Association between sleep disturbance in Alzheimer’s disease patients and burden on and health status of their caregivers

BACKGROUND: Sleep disturbance in Alzheimer’s disease (AD) patients may have a negative impact not only on patients themselves but also on the physical and mental health of their caregivers. Detailed analysis of these issues is lacking. OBJECTIVE: This study investigated the association between sleep...

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Autores principales: Okuda, Shoki, Tetsuka, Jumpei, Takahashi, Kenichi, Toda, Yasuo, Kubo, Takekazu, Tokita, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517338/
https://www.ncbi.nlm.nih.gov/pubmed/30968171
http://dx.doi.org/10.1007/s00415-019-09286-0
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author Okuda, Shoki
Tetsuka, Jumpei
Takahashi, Kenichi
Toda, Yasuo
Kubo, Takekazu
Tokita, Shigeru
author_facet Okuda, Shoki
Tetsuka, Jumpei
Takahashi, Kenichi
Toda, Yasuo
Kubo, Takekazu
Tokita, Shigeru
author_sort Okuda, Shoki
collection PubMed
description BACKGROUND: Sleep disturbance in Alzheimer’s disease (AD) patients may have a negative impact not only on patients themselves but also on the physical and mental health of their caregivers. Detailed analysis of these issues is lacking. OBJECTIVE: This study investigated the association between sleep disturbance in AD patients and the burden on, and health status of, their caregivers in Japan. METHODS: We conducted a cross-sectional web-based questionnaire survey among caregivers of AD patients with insomnia symptoms in Japan. Demographic data and Sleep Disorders Inventory (SDI) scores for patients, caregiver burden (Burden Index of Caregivers-11 [BIC-11]) and health status, including Pittsburgh Sleep Quality Index, Patient Health Questionnaire-9, and 12-Item Short Form Health Survey v2, were collected. Multivariate analysis was used to examine the association between the burden and health status of caregivers and sleep disturbance in their care recipients with AD. RESULTS: A total of 496 caregivers of AD patients with insomnia symptoms were examined in this study. We found that the BIC-11 total score increased as the SDI score increased, indicating a significant positive association, even after adjusting for confounding factors. We also found an association between sleep disturbances of AD patients and health of caregivers (sleep quality, depression, and physical/mental quality of life). CONCLUSION: This study demonstrated that sleep disturbance in AD patients was associated with an increased burden and poorer health status of caregivers. Our findings highlight the importance of sleep management in AD patients. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00415-019-09286-0) contains supplementary material, which is available to authorized users.
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spelling pubmed-65173382019-05-28 Association between sleep disturbance in Alzheimer’s disease patients and burden on and health status of their caregivers Okuda, Shoki Tetsuka, Jumpei Takahashi, Kenichi Toda, Yasuo Kubo, Takekazu Tokita, Shigeru J Neurol Original Communication BACKGROUND: Sleep disturbance in Alzheimer’s disease (AD) patients may have a negative impact not only on patients themselves but also on the physical and mental health of their caregivers. Detailed analysis of these issues is lacking. OBJECTIVE: This study investigated the association between sleep disturbance in AD patients and the burden on, and health status of, their caregivers in Japan. METHODS: We conducted a cross-sectional web-based questionnaire survey among caregivers of AD patients with insomnia symptoms in Japan. Demographic data and Sleep Disorders Inventory (SDI) scores for patients, caregiver burden (Burden Index of Caregivers-11 [BIC-11]) and health status, including Pittsburgh Sleep Quality Index, Patient Health Questionnaire-9, and 12-Item Short Form Health Survey v2, were collected. Multivariate analysis was used to examine the association between the burden and health status of caregivers and sleep disturbance in their care recipients with AD. RESULTS: A total of 496 caregivers of AD patients with insomnia symptoms were examined in this study. We found that the BIC-11 total score increased as the SDI score increased, indicating a significant positive association, even after adjusting for confounding factors. We also found an association between sleep disturbances of AD patients and health of caregivers (sleep quality, depression, and physical/mental quality of life). CONCLUSION: This study demonstrated that sleep disturbance in AD patients was associated with an increased burden and poorer health status of caregivers. Our findings highlight the importance of sleep management in AD patients. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00415-019-09286-0) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2019-04-09 2019 /pmc/articles/PMC6517338/ /pubmed/30968171 http://dx.doi.org/10.1007/s00415-019-09286-0 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Communication
Okuda, Shoki
Tetsuka, Jumpei
Takahashi, Kenichi
Toda, Yasuo
Kubo, Takekazu
Tokita, Shigeru
Association between sleep disturbance in Alzheimer’s disease patients and burden on and health status of their caregivers
title Association between sleep disturbance in Alzheimer’s disease patients and burden on and health status of their caregivers
title_full Association between sleep disturbance in Alzheimer’s disease patients and burden on and health status of their caregivers
title_fullStr Association between sleep disturbance in Alzheimer’s disease patients and burden on and health status of their caregivers
title_full_unstemmed Association between sleep disturbance in Alzheimer’s disease patients and burden on and health status of their caregivers
title_short Association between sleep disturbance in Alzheimer’s disease patients and burden on and health status of their caregivers
title_sort association between sleep disturbance in alzheimer’s disease patients and burden on and health status of their caregivers
topic Original Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517338/
https://www.ncbi.nlm.nih.gov/pubmed/30968171
http://dx.doi.org/10.1007/s00415-019-09286-0
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