How to detect and correct myocardial creep in myocardial perfusion imaging using Rubidium-82 PET?

Reliability of myocardial blood flow (MBF) quantification in myocardial perfusion imaging (MPI) using PET can majorly be affected by the occurrence of myocardial creep when using pharmacologically induced stress. In this paper, we provide instructions on how to detect and correct for myocardial cree...

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Detalles Bibliográficos
Autores principales: Koenders, S. S., van Dijk, J. D., Jager, P. L., Ottervanger, J. P., Slump, C. H., van Dalen, J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Technical Corner
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517341/
https://www.ncbi.nlm.nih.gov/pubmed/30788759
http://dx.doi.org/10.1007/s12350-019-01650-x
Descripción
Sumario:Reliability of myocardial blood flow (MBF) quantification in myocardial perfusion imaging (MPI) using PET can majorly be affected by the occurrence of myocardial creep when using pharmacologically induced stress. In this paper, we provide instructions on how to detect and correct for myocardial creep. For example, in each time frame of the PET images the myocardium contour and the observed activity have to be compared to check for misalignments. In addition, we provide an overview of the functionality of commonly used software packages to perform this quality control step as not all software packages currently provide this functionality. Furthermore, important clinical considerations to obtain accurate MBF measurements are given.

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