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MicroRNA-126 regulates Hypoxia-Inducible Factor-1α which inhibited migration, proliferation, and angiogenesis in replicative endothelial senescence
Whereas a healthy endothelium maintains physiological vascular functions, endothelial damage contributes to the development of cardiovascular diseases. Endothelial senescence is the main determinant of endothelial dysfunction and thus of age-related cardiovascular disease. The objective of this stud...
Autores principales: | Alique, Matilde, Bodega, Guillermo, Giannarelli, Chiara, Carracedo, Julia, Ramírez, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517399/ https://www.ncbi.nlm.nih.gov/pubmed/31089163 http://dx.doi.org/10.1038/s41598-019-43689-3 |
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