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Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis
The gut commensal Bacteroides fragilis or its capsular polysaccharide A (PSA) can prevent various peripheral and CNS sterile inflammatory disorders. Fatal herpes simplex encephalitis (HSE) results from immune pathology caused by uncontrolled invasion of the brainstem by inflammatory monocytes and ne...
Autores principales: | Ramakrishna, Chandran, Kujawski, Maciej, Chu, Hiutung, Li, Lin, Mazmanian, Sarkis K., Cantin, Edouard M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517419/ https://www.ncbi.nlm.nih.gov/pubmed/31089128 http://dx.doi.org/10.1038/s41467-019-09884-6 |
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