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Genetic Variants of PICALM rs541458 Modulate Brain Spontaneous Activity in Older Adults With Amnestic Mild Cognitive Impairment

Background: Phosphatidylinositol binding clathrin assembly protein (PICALM) rs541458 C allele has been identified and validated to be associated with a reduction of Alzheimer's disease (AD) risk. Nevertheless, the exact mechanisms through which the variant exert its disease-relevant association...

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Detalles Bibliográficos
Autores principales:	Zhuang, Liying, Liu, Xiaoyan, Shi, Yongmei, Liu, Xiaoli, Luo, Benyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517502/ https://www.ncbi.nlm.nih.gov/pubmed/31133980 http://dx.doi.org/10.3389/fneur.2019.00494

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