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Alpha-Herpesvirus Thymidine Kinase Genes Mediate Viral Virulence and Are Potential Therapeutic Targets

Alpha-herpesvirus thymidine kinase (TK) genes are virulence-related genes and are nonessential for viral replication; they are often preferred target genes for the construction of gene-deleted attenuated vaccines and genetically engineered vectors for inserting and expressing foreign genes. The enzy...

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Detalles Bibliográficos
Autores principales:	Xie, Ying, Wu, Liping, Wang, Mingshu, Cheng, Anchun, Yang, Qiao, Wu, Ying, Jia, Renyong, Zhu, Dekang, Zhao, XinXin, Chen, Shun, Liu, Mafeng, Zhang, Shaqiu, Wang, Yin, Xu, Zhiwen, Chen, Zhengli, Zhu, Ling, Luo, Qihui, Liu, Yunya, Yu, Yanling, Zhang, Ling, Chen, Xiaoyue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517553/ https://www.ncbi.nlm.nih.gov/pubmed/31134006 http://dx.doi.org/10.3389/fmicb.2019.00941

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