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Metabolic effects of orally administered small-molecule agonists of GPR55 and GPR119 in multiple low-dose streptozotocin-induced diabetic and incretin-receptor-knockout mice

AIMS/HYPOTHESIS: Abnormal cannabidiol (Abn-CBD) and AS-1269574 are potent selective agonists for GPR55 and GPR119, respectively. The present study evaluated the actions and ability of these small-molecule agonists to counteract experimental diabetes in mice. METHODS: Diabetes was induced in NIH Swis...

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Detalles Bibliográficos
Autores principales:	McKillop, Aine M., Moran, Brian M., Abdel-Wahab, Yasser H. A., Gormley, Noella M., Flatt, Peter R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518089/ https://www.ncbi.nlm.nih.gov/pubmed/27677765 http://dx.doi.org/10.1007/s00125-016-4108-z

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