Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle

AIMS/HYPOTHESIS: Understanding the molecular networks controlling ectopic lipid deposition and insulin responsiveness in skeletal muscle is essential for developing new strategies to treat type 2 diabetes. We recently identified serine/threonine protein kinase 25 (STK25) as a critical regulator of l...

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Detalles Bibliográficos
Autores principales: Chursa, Urszula, Nuñez-Durán, Esther, Cansby, Emmelie, Amrutkar, Manoj, Sütt, Silva, Ståhlman, Marcus, Olsson, Britt-Marie, Borén, Jan, Johansson, Maria E., Bäckhed, Fredrik, Johansson, Bengt R., Sihlbom, Carina, Mahlapuu, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518105/
https://www.ncbi.nlm.nih.gov/pubmed/27981357
http://dx.doi.org/10.1007/s00125-016-4171-5

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