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Activation of the Alternate Renin-Angiotensin System Correlates with the Clinical Status in Human Cirrhosis and Corrects Post Liver Transplantation

Introduction: Recent animal studies have shown that the alternate renin-angiotensin system (RAS) consisting of angiotensin-converting enzyme 2 (ACE2), angiotensin-(1–7) (Ang-(1–7)) and the Mas receptor is upregulated in cirrhosis and contributes to splanchnic vasodilatation and portal hypertension....

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Detalles Bibliográficos
Autores principales: Casey, Stephen, Schierwagen, Robert, Mak, Kai Yan, Klein, Sabine, Uschner, Frank, Jansen, Christian, Praktiknjo, Michael, Meyer, Carsten, Thomas, Daniel, Herath, Chandana, Jones, Robert, Trebicka, Jonel, Angus, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518205/
https://www.ncbi.nlm.nih.gov/pubmed/30934723
http://dx.doi.org/10.3390/jcm8040419