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Late re-activation of Coats disease
PURPOSE: To report case of Coats disease with the longest known interval of disease quiescence prior to first reactivation (17 years). OBSERVATION: A 25-year-old male was regularly followed for Coats disease since age 4. After initial treatment with cryoablation, disease quiescence was achieved at a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518316/ https://www.ncbi.nlm.nih.gov/pubmed/31193172 http://dx.doi.org/10.1016/j.ajoc.2019.100458 |
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author | Lertjirachai, Itsara Wood, Edward H. Moinuddin, Omar Drenser, Kimberly A. |
author_facet | Lertjirachai, Itsara Wood, Edward H. Moinuddin, Omar Drenser, Kimberly A. |
author_sort | Lertjirachai, Itsara |
collection | PubMed |
description | PURPOSE: To report case of Coats disease with the longest known interval of disease quiescence prior to first reactivation (17 years). OBSERVATION: A 25-year-old male was regularly followed for Coats disease since age 4. After initial treatment with cryoablation, disease quiescence was achieved at age 8. The disease activity was well controlled for 17 years after which he developed decreased vision in the right eye at age 25. Late reactivation of Coats disease was diagnosed and multiple treatments ensued. Despite aggressive therapy, the patient experienced progressive exudation warranting surgical management and eventually developed neovascular glaucoma. CONCLUSION: Once diagnosed with Coats disease, lifelong monitoring is essential to early detection and treatment of potential disease reactivation. The interval between disease quiescence and reactivation is variable, with this case representing the longest known interval of disease quiescence prior to first reactivation (17 years). |
format | Online Article Text |
id | pubmed-6518316 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-65183162019-05-21 Late re-activation of Coats disease Lertjirachai, Itsara Wood, Edward H. Moinuddin, Omar Drenser, Kimberly A. Am J Ophthalmol Case Rep Case Report PURPOSE: To report case of Coats disease with the longest known interval of disease quiescence prior to first reactivation (17 years). OBSERVATION: A 25-year-old male was regularly followed for Coats disease since age 4. After initial treatment with cryoablation, disease quiescence was achieved at age 8. The disease activity was well controlled for 17 years after which he developed decreased vision in the right eye at age 25. Late reactivation of Coats disease was diagnosed and multiple treatments ensued. Despite aggressive therapy, the patient experienced progressive exudation warranting surgical management and eventually developed neovascular glaucoma. CONCLUSION: Once diagnosed with Coats disease, lifelong monitoring is essential to early detection and treatment of potential disease reactivation. The interval between disease quiescence and reactivation is variable, with this case representing the longest known interval of disease quiescence prior to first reactivation (17 years). Elsevier 2019-04-25 /pmc/articles/PMC6518316/ /pubmed/31193172 http://dx.doi.org/10.1016/j.ajoc.2019.100458 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Lertjirachai, Itsara Wood, Edward H. Moinuddin, Omar Drenser, Kimberly A. Late re-activation of Coats disease |
title | Late re-activation of Coats disease |
title_full | Late re-activation of Coats disease |
title_fullStr | Late re-activation of Coats disease |
title_full_unstemmed | Late re-activation of Coats disease |
title_short | Late re-activation of Coats disease |
title_sort | late re-activation of coats disease |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518316/ https://www.ncbi.nlm.nih.gov/pubmed/31193172 http://dx.doi.org/10.1016/j.ajoc.2019.100458 |
work_keys_str_mv | AT lertjirachaiitsara latereactivationofcoatsdisease AT woodedwardh latereactivationofcoatsdisease AT moinuddinomar latereactivationofcoatsdisease AT drenserkimberlya latereactivationofcoatsdisease |