Glucose Drives Growth Factor–Independent Esophageal Cancer Proliferation via Phosphohistidine–Focal Adhesion Kinase Signaling

BACKGROUND & AIMS: Most targeted therapies against cancer are designed to block growth factor–stimulated oncogenic growth. However, response rates are low, and resistance to therapy is high. One mechanism might relate to the ability of tumor cells to induce growth factor–independent proliferatio...

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Detalles Bibliográficos
Autores principales: Zhang, Jianliang, Gelman, Irwin H., Katsuta, Eriko, Liang, Yuanzi, Wang, Xue, Li, Jun, Qu, Jun, Yan, Li, Takabe, Kazuaki, Hochwald, Steven N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518323/
https://www.ncbi.nlm.nih.gov/pubmed/30836148
http://dx.doi.org/10.1016/j.jcmgh.2019.02.009

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