Co-circulation of multiple subtypes of enterovirus A71 (EV- A71) genotype C, including novel recombinants characterised by use of whole genome sequencing (WGS), Denmark 2016

In Europe, enterovirus A71 (EV-A71) has primarily been associated with sporadic cases of neurological disease. The recent emergence of new genotypes and larger outbreaks with severely ill patients demonstrates a potential for the spread of new, highly pathogenic EV-A71 strains. Detection and charact...

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Autores principales: Midgley, Sofie E, Nielsen, Astrid G, Trebbien, Ramona, Poulsen, Mille W., Andersen, Peter H, Fischer, Thea K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2017
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518347/
https://www.ncbi.nlm.nih.gov/pubmed/28681718
http://dx.doi.org/10.2807/1560-7917.ES.2017.22.26.30565
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author Midgley, Sofie E
Nielsen, Astrid G
Trebbien, Ramona
Poulsen, Mille W.
Andersen, Peter H
Fischer, Thea K
author_facet Midgley, Sofie E
Nielsen, Astrid G
Trebbien, Ramona
Poulsen, Mille W.
Andersen, Peter H
Fischer, Thea K
author_sort Midgley, Sofie E
collection PubMed
description In Europe, enterovirus A71 (EV-A71) has primarily been associated with sporadic cases of neurological disease. The recent emergence of new genotypes and larger outbreaks with severely ill patients demonstrates a potential for the spread of new, highly pathogenic EV-A71 strains. Detection and characterisation of these new emerging EV variants is challenging as standard EV assays may not be adequate, necessitating the use of whole genome analysis.
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spelling pubmed-65183472019-06-03 Co-circulation of multiple subtypes of enterovirus A71 (EV- A71) genotype C, including novel recombinants characterised by use of whole genome sequencing (WGS), Denmark 2016 Midgley, Sofie E Nielsen, Astrid G Trebbien, Ramona Poulsen, Mille W. Andersen, Peter H Fischer, Thea K Euro Surveill Rapid Communication In Europe, enterovirus A71 (EV-A71) has primarily been associated with sporadic cases of neurological disease. The recent emergence of new genotypes and larger outbreaks with severely ill patients demonstrates a potential for the spread of new, highly pathogenic EV-A71 strains. Detection and characterisation of these new emerging EV variants is challenging as standard EV assays may not be adequate, necessitating the use of whole genome analysis. European Centre for Disease Prevention and Control (ECDC) 2017-06-29 /pmc/articles/PMC6518347/ /pubmed/28681718 http://dx.doi.org/10.2807/1560-7917.ES.2017.22.26.30565 Text en This article is copyright of The Authors, 2017. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Midgley, Sofie E
Nielsen, Astrid G
Trebbien, Ramona
Poulsen, Mille W.
Andersen, Peter H
Fischer, Thea K
Co-circulation of multiple subtypes of enterovirus A71 (EV- A71) genotype C, including novel recombinants characterised by use of whole genome sequencing (WGS), Denmark 2016
title Co-circulation of multiple subtypes of enterovirus A71 (EV- A71) genotype C, including novel recombinants characterised by use of whole genome sequencing (WGS), Denmark 2016
title_full Co-circulation of multiple subtypes of enterovirus A71 (EV- A71) genotype C, including novel recombinants characterised by use of whole genome sequencing (WGS), Denmark 2016
title_fullStr Co-circulation of multiple subtypes of enterovirus A71 (EV- A71) genotype C, including novel recombinants characterised by use of whole genome sequencing (WGS), Denmark 2016
title_full_unstemmed Co-circulation of multiple subtypes of enterovirus A71 (EV- A71) genotype C, including novel recombinants characterised by use of whole genome sequencing (WGS), Denmark 2016
title_short Co-circulation of multiple subtypes of enterovirus A71 (EV- A71) genotype C, including novel recombinants characterised by use of whole genome sequencing (WGS), Denmark 2016
title_sort co-circulation of multiple subtypes of enterovirus a71 (ev- a71) genotype c, including novel recombinants characterised by use of whole genome sequencing (wgs), denmark 2016
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518347/
https://www.ncbi.nlm.nih.gov/pubmed/28681718
http://dx.doi.org/10.2807/1560-7917.ES.2017.22.26.30565
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