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Purine-rich low complexity regions are potential RNA binding hubs in the human genome

Many long noncoding RNAs are bound to the chromatin and some of these interactions are mediated by triple helices. It is usually assumed that a transcript can form triplexes with a distinct set of genomic loci also known as triplex target sites (TTSs). Here we performed computational analyses of the...

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Detalles Bibliográficos
Autores principales: Antonov, Ivan, Medvedeva, Yulia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518440/
https://www.ncbi.nlm.nih.gov/pubmed/31131080
http://dx.doi.org/10.12688/f1000research.13522.2