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Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness
Background: Mannose-binding lectin (MBL) is an innate immune protein with strong biologic plausibility for protecting against influenza virus-related sepsis and bacterial co-infection. In an autopsy cohort of 105 influenza-infected young people, carriage of the deleterious MBL gene MBL2_Gly54Asp(“B”...
Autores principales: | Levy, Emily R., Yip, Wai-Ki, Super, Michael, Ferdinands, Jill M., Mistry, Anushay J., Newhams, Margaret M., Zhang, Yu, Su, Helen C., McLaughlin, Gwenn E., Sapru, Anil, Loftis, Laura L., Weiss, Scott L., Hall, Mark W., Cvijanovich, Natalie, Schwarz, Adam, Tarquinio, Keiko M., Mourani, Peter M., Randolph, Adrienne G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518443/ https://www.ncbi.nlm.nih.gov/pubmed/31139182 http://dx.doi.org/10.3389/fimmu.2019.01005 |
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