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La Crosse virus: a scoping review of the global evidence

Urbanisation and climate change are altering the pattern of California serogroup viruses in North America. As La Crosse virus (LACV) is the most pathogenic of the California serogroup, it is important to identify changes in distribution, transmission and pathogenesis. A scoping review (ScR) was prio...

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Autores principales: Harding, S., Greig, J., Mascarenhas, M., Young, I., Waddell, L. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518580/
https://www.ncbi.nlm.nih.gov/pubmed/30516125
http://dx.doi.org/10.1017/S0950268818003096
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author Harding, S.
Greig, J.
Mascarenhas, M.
Young, I.
Waddell, L. A.
author_facet Harding, S.
Greig, J.
Mascarenhas, M.
Young, I.
Waddell, L. A.
author_sort Harding, S.
collection PubMed
description Urbanisation and climate change are altering the pattern of California serogroup viruses in North America. As La Crosse virus (LACV) is the most pathogenic of the California serogroup, it is important to identify changes in distribution, transmission and pathogenesis. A scoping review (ScR) was prioritised to summarise the global evidence on LACV. A comprehensive search strategy was used, identified references were screened for relevance and relevant articles were characterised. Each step was conducted by two independent reviewers using pre-tested forms. Analysis identified areas of research saturation and gaps. The ScR included 481 research articles that were mostly journal articles (78.2%) conducted in North America (90.9%) from 1969 to 2016. Most evidence focused on epidemiology (44.9%), virus characteristics (25.8%), transmission conditions (18.7%) and pathogenesis of LACV in hosts (18.3%). Fewer studies evaluated the accuracy of diagnostic tests (8.7%), the efficacy of treatments (3.5%), prevention and control strategies (3.1%), the economic burden of infection (0.6%) and social impact (0.2%) of LACV. None of the literature predicted the impact of climate change on LACV, nor were any cases reported in Canada. These findings are intended to guide research to close knowledge gaps and inform evidence-based decisions surrounding activities for the prevention and control of LACV.
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spelling pubmed-65185802019-06-04 La Crosse virus: a scoping review of the global evidence Harding, S. Greig, J. Mascarenhas, M. Young, I. Waddell, L. A. Epidemiol Infect Original Paper Urbanisation and climate change are altering the pattern of California serogroup viruses in North America. As La Crosse virus (LACV) is the most pathogenic of the California serogroup, it is important to identify changes in distribution, transmission and pathogenesis. A scoping review (ScR) was prioritised to summarise the global evidence on LACV. A comprehensive search strategy was used, identified references were screened for relevance and relevant articles were characterised. Each step was conducted by two independent reviewers using pre-tested forms. Analysis identified areas of research saturation and gaps. The ScR included 481 research articles that were mostly journal articles (78.2%) conducted in North America (90.9%) from 1969 to 2016. Most evidence focused on epidemiology (44.9%), virus characteristics (25.8%), transmission conditions (18.7%) and pathogenesis of LACV in hosts (18.3%). Fewer studies evaluated the accuracy of diagnostic tests (8.7%), the efficacy of treatments (3.5%), prevention and control strategies (3.1%), the economic burden of infection (0.6%) and social impact (0.2%) of LACV. None of the literature predicted the impact of climate change on LACV, nor were any cases reported in Canada. These findings are intended to guide research to close knowledge gaps and inform evidence-based decisions surrounding activities for the prevention and control of LACV. Cambridge University Press 2018-12-05 /pmc/articles/PMC6518580/ /pubmed/30516125 http://dx.doi.org/10.1017/S0950268818003096 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.
spellingShingle Original Paper
Harding, S.
Greig, J.
Mascarenhas, M.
Young, I.
Waddell, L. A.
La Crosse virus: a scoping review of the global evidence
title La Crosse virus: a scoping review of the global evidence
title_full La Crosse virus: a scoping review of the global evidence
title_fullStr La Crosse virus: a scoping review of the global evidence
title_full_unstemmed La Crosse virus: a scoping review of the global evidence
title_short La Crosse virus: a scoping review of the global evidence
title_sort la crosse virus: a scoping review of the global evidence
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518580/
https://www.ncbi.nlm.nih.gov/pubmed/30516125
http://dx.doi.org/10.1017/S0950268818003096
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