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Role of TRPC1 channels in pressure-mediated activation of airway remodeling

BACKGROUND: Bronchoconstriction and cough, a characteristic of the asthmatic response, leads to development of compressive stresses in the airway wall. We hypothesized that progressively pathological high mechanical stress could act on mechanosensitive cation channels, such as transient receptor pot...

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Detalles Bibliográficos
Autores principales: Li, Na, He, Ye, Yang, Gang, Yu, Qian, Li, Minchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518742/
https://www.ncbi.nlm.nih.gov/pubmed/31092255
http://dx.doi.org/10.1186/s12931-019-1050-x